Completion marks are earned by completing specific objectives in The Binding of Isaac: Rebirth. As you complete these objectives, the post-it note on the character select screen fills up with Completion Marks. If objectives are completed in Normal mode, the completion marks are solid black. If objectives are completed in Hard mode, the completion marks are outlined in red. If a completion mark is earned in Hard mode without first earning it in Normal mode, the game will count both the normal mark and the Hard mode mark as unlocked.
More information about completion marks in general can be found in the vanilla page.
Up to 3 Greed mode completion marks can be obtained in a single run using 2 or more items that revive you as a different character – alongside 2 Forget Me Nows.
Completion marks are earned by completing specific objectives in The Binding of Isaac: Rebirth. As you complete these objectives, the post-it note on the character select screen fills up with Completion Marks. If objectives are completed in Normal mode, the completion marks are solid black.
Completion marks and Achievements cannot be earned (except for the Achievements earned for completing Victory Laps). The effects of all Pills are re-randomized. Some items are lost upon starting a Victory Lap.
Unlike other completion marks, defeating Delirium does not add a mark to the post-it note. Instead, the note will become tattered (with blood on Hard mode). If no other bosses have been encountered during the run, Delirium is unable to transform. The Void on any run.
Delirium is a surprisingly simple process, it requires imagining the boss rooms as being 2x2 boss rooms. If the 2x2 boss room would be able to exist where it is without having doors to any other rooms, then it is very likely that boss room will contain Delirium.
If The Lamb is shooting projectiles and you damage it over half of its health, it will continue to fire until dead or it has finished its attack. Killing the body in around 5 seconds will make the body stand inside of the chest, making you unable to reach it (and end the game).
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